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INTERNATIONAL CONGRESS OF

CancerGenetics

• A review of evaluation and management of lung cancer in patients with interstitial lung disease

• Mahdiyeh Mirzalou,^1,* Marziyeh Mirzalou,²
  1. Bachelor student of microbiology, Islamic Azad Faculty of Biosciences and Technologies, Marand, Marand, Iran
  2. Bachelor student of microbiology, Islamic Azad Faculty of Biosciences and Technologies, Marand, Marand, Iran
  
  
  
• Introduction: Patients with interstitial lung disease increase the risk of developing lung cancer, the consequences and possible pulmonary complications due to invasive methods and toxicity caused by lung cancer treatment, which should be done with careful and potential management decisions.
• Methods: In order to identify studies aimed at evaluating and managing lung cancer in patients with interstitial lung disease, this systematic review was conducted by searching Google Scholar, Science Direct, PubMed databases based on the keywords Lung cancer, Interstitial lung disease, Treatment. After reviewing the summary of the articles and checking the title, irrelevant articles were removed and the full text of the articles was searched and the articles related to the topic were included in the study.
• Results: According to studies, symptom-based assessment for lung cancer in patients with interstitial disease overlaps with lung cancer symptoms and often includes shortness of breath, cough, and functional limitations. Physical examination findings and other symptoms can rarely occur as a direct consequence of interstitial lung disease; Among them, hemoptysis, weight loss, chest pain, obesity, pleural effusion and lymphadenopathy are significant. Therefore, these features should prompt investigation of lung cancer and further possible tests to evaluate possible causes.
• Conclusion: The risk of complications and mortality in patients with interstitial lung disease will be higher compared to patients with lung cancer who do not suffer from this disease, and the treatment should be proportional to the individual risks associated with the diagnosis and severity of the patient's interstitial lung disease.
• Keywords: Lung cancer, Interstitial lung disease, Treatment